Supervisor’s research interests

We try to crosslink complex genomic and transcriptomic patterns with human pathology to develop new generation of molecular diagnostic tests. Our primary expertise is within oncology where we developed several platforms predicting cancer drug efficacies using molecular pathway activation data deduced using patient’s high throughput molecular profiles.

Research highlights

Most of our projects are international collaborations with the top biomedical institutes in all around the world.
We believe a good student project in our field should lead to a paper in a highly ranked journal or two.

Main publications

• RNA sequencing for research and diagnostics in clinical oncology. Buzdin A, Sorokin M, Garazha A, Glusker A, Aleshin A, Poddubskaya E, Sekacheva M, Kim E, Gaifullin N, Giese A, Seryakov A, Rumiantsev P, Moshkovskii S, Moiseev A. Semin Cancer Biol. 2020 Feb;60:311-323. doi: 10.1016/j.semcancer.2019.07.010
• Atlas of RNA sequencing profiles for normal human tissues. Suntsova M, Gaifullin N, Allina D, Reshetun A, Li X, Mendeleeva L, Surin V, Sergeeva A, Spirin P, Prassolov V, Morgan A, Garazha A, Sorokin M, Buzdin A. Sci Data. 2019 Apr 23;6(1):36. doi: 10.1038/s41597-019-0043-4.
• Mutation Enrichment and Transcriptomic Activation Signatures of 419 Molecular Pathways in Cancer. Zolotovskaia MA, Tkachev VS, Seryakov AP, Kuzmin DV, Kamashev DE, Sorokin MI, Roumiantsev SA, Buzdin AA. Cancers (Basel). 2020 Jan 22;12(2). pii: E271. doi: 10.3390/cancers12020271.