Supervisor’s research interests

• Human induced pluripotent stem cells
• Direct reprogramming of human somatic cells
• Genome editing using CRISPR/Cas9 methods
• CRISPR-a screening of reprogramming factors
• Single cell RNA-seq analysis

Research highlights

• A well-equipped scientific laboratory, which has almost all the necessary tools to perform work on the declared topics
• Young friendly team of like-minded people, favorable atmosphere of creativity
• Setting up the appropriate level of research work for publication in international scientific journals

Main publications

Full list can be found here.

• Dashinimaev EB et al. Neurons Derived from Induced Pluripotent Stem Cells of Patients with Down Syndrome Reproduce Early Stages of Alzheimer's Disease Type Pathology in vitro. J Alzheimers Dis. 2017;56(2):835-847. doi: 10.3233/JAD-160945.
• Artyukhov AS, Dashinimaev EB et al. New genes for accurate normalization of qRT-PCR results in study of iPS and iPS-derived cells. Gene. 2017 Aug 30;626:234-240. doi: 10.1016/j.gene.2017.05.045.
• Artyuhov AS, Dashinimaev EB et al. Detection of small numbers of iPSCs in different heterogeneous cell mixtures with highly sensitive droplet digital PCR. Mol Biol Rep. 2019 Dec;46(6):6675-6683. doi:10.1007/s11033-019-05100-2.